For close to 400 years, the painting was closed off to the world. For the past 124 years, millions of visitors walked by without noticing an intriguing scene covered with centuries of grime.
Only now, the Vatican says a detail in a newly cleaned 15th century fresco shows what may be one of the first European depictions of Native Americans.
The fresco, The Resurrection, was painted by the Renaissance master Pinturicchio in 1494
